HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Metabolic syndrome and shoulder arthroplasty: epidemiology and peri-operative outcomes.

AbstractPURPOSE:
Little is known about metabolic syndrome in the peri-operative shoulder surgery setting. We sought to determine the prevalence of metabolic syndrome in patients undergoing shoulder arthroplasty, and to characterize its relationship with in-hospital adverse events, prolonged length of stay, and non-routine disposition.
METHODS:
Using discharge records from the 2002-2011 Nationwide Inpatient Sample, temporal trends were assessed and multivariable logistic regression modeling was used to measure the association of metabolic syndrome with peri-operative outcomes.
RESULTS:
The prevalence of metabolic syndrome increased by 257 % from 2002 to 2011 (4.2 to 15.0 %). Metabolic syndrome was associated with increased aggregate morbidity (OR 1.34, 95 % CI 1.30-1.38), including acute renal failure (OR 1.51, 95 % CI 1.41-1.63), surgical site infection (OR 1.41, 95 % CI 1.16-1.71), myocardial infarction (OR 1.32, 95 % CI 1.12-1.55), acute posthemorrhagic anemia (OR 1.30, 95 % CI 1.26-1.34), and pulmonary embolism (OR 1.27, 95 % CI 1.06-1.52). It was also associated with prolonged hospital stay (OR 1.13, 95 % CI 1.10-1.16), non-homebound discharge (OR 1.29, 95 % CI 1.26-1.32), and increased blood transfusion use (OR 1.09, 95 % CI 1.06-1.13).
CONCLUSIONS:
Metabolic syndrome is increasing rapidly among shoulder arthroplasty patients and is associated with considerable peri-operative morbidity and resource utilization. Greater awareness of metabolic syndrome and its health consequences may contribute to improvements in the peri-operative management of shoulder arthroplasty patients.
AuthorsAustin B Murphy, Mariano E Menendez, Shawna L Watson, Brent A Ponce
JournalInternational orthopaedics (Int Orthop) Vol. 40 Issue 9 Pg. 1927-33 (Sep 2016) ISSN: 1432-5195 [Electronic] Germany
PMID27138608 (Publication Type: Journal Article)
Topics
  • Arthroplasty, Replacement
  • Humans
  • Length of Stay
  • Metabolic Syndrome
  • Postoperative Complications
  • Retrospective Studies
  • Risk Factors
  • Shoulder
  • Shoulder Joint

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: