Abstract | CONCLUSION: The findings suggest that a pectoralis major flap combined with a free flap is a safe and reliable method of reconstruction after total pharyngolaryngectomy; with this technique, one can help these patients remain disease free, with normal swallowing function, for a relatively acceptable survival duration. OBJECTIVES: To determine the functional and oncological outcomes of a combined flap for the extensive defects after total pharyngolaryngectomy in patients with advanced squamous cell carcinoma of the hypopharynx (SCCHP). METHOD: This study determined the perioperative morbidity and functional and oncologic outcomes of 21 patients with advanced SCCHP who underwent total laryngopharyngectomy and reconstruction using a combination of a pectoralis major flap and a free flap. RESULTS: The free flap and pectoralis major flap were used to reconstruct the defects for all 21 patients. Fourteen patients were reconstructed with jejunal free flaps and pectoralis major flaps; in the remaining seven patients, anterolateral thigh flaps and pectoralis major flaps were used. All the combined flaps worked well, and patients recovered normal swallowing function a mean 19.4 days after surgery. After an overall mean follow-up time of 31.3 months, 30% of patients were still alive at the time of this analysis, with no evidence of disease.
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Authors | Caiyun Zhang, Minhui Zhu, Mengjie Chen, Donghui Chen, Shicai Chen, Hongliang Zheng |
Journal | Acta oto-laryngologica
(Acta Otolaryngol)
Vol. 136
Issue 8
Pg. 841-6
(Aug 2016)
ISSN: 1651-2251 [Electronic] England |
PMID | 27066846
(Publication Type: Journal Article)
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Topics |
- Aged
- Carcinoma, Squamous Cell
(surgery)
- Female
- Humans
- Hypopharyngeal Neoplasms
(surgery)
- Laryngectomy
- Male
- Middle Aged
- Pharyngectomy
- Plastic Surgery Procedures
(methods)
- Recovery of Function
- Retrospective Studies
- Surgical Flaps
- Treatment Outcome
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