Abstract | AIM: To study the ultrastructural localization of five marker enzymes (ALPase, ACPase, G6Pase, TPPase and CCOase) in gastric cancer signet ring cells to demonstrate their biologic behaviors. METHODS: Five marker enzymes were examined in signet ring cells of seven gastric cancer patients by ultrastructural enzyme cytochemical techniques. RESULTS: The number of corresponding organelles and the activities of marker enzymes, especially ACPase and TPPase, increased, leading to stronger mucus synthesis, secretion and digestion in gastric cancer signet ring cells. There was a lack of collagenous fibers in the stroma around the cancer nests. CONCLUSION:
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Authors | G L Yang, Y M Dong, W D Du, Y H Su, H Zhang, J F Wu, D B Wang, A L Xu |
Journal | World journal of gastroenterology
(World J Gastroenterol)
Vol. 3
Issue 2
Pg. 86
(Jun 15 1997)
ISSN: 1007-9327 [Print] United States |
PMID | 27041951
(Publication Type: Journal Article)
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