Myoepithelioma-like Tumor of the Vulvar Region Presenting as a Nonmyxoid Spindle-Cell Neoplasm: A Potential Histologic Mimicker of Solitary Fibrous Tumor.

Abstract

A new entity termed "myoepithelioma-like tumor of the vulvar region (MELTVR)" has been proposed as a rare mesenchymal neoplasm of the vulvar area. Histologically, MELTVRs are usually similar to soft tissue myoepitheliomas; however, they have a characteristic immunoprofile, including positivity for estrogen receptor and negativity for S100 protein, and loss of SMARCB1 expression. In this first known case report of MELTVR, the authors present a case of MELTVR that was histologically categorized in a nonmyxoid spindle-cell tumor group and resembled solitary fibrous tumor rather than soft tissue myoepithelioma.

• Authors: Yo Kaku, Keisuke Goto, Kenji Kabashima
• Journal: The American Journal of dermatopathology (Am J Dermatopathol) Vol. 38 Issue 7 Pg. e87-9 (Jul 2016) ISSN: 1533-0311 [Electronic] United States
• PMID: 26959696 (Publication Type: Case Reports, Journal Article)

Chemical References

• Biomarkers, Tumor

Topics

• Adult
• Biomarkers, Tumor (analysis)
• Biopsy
• Diagnosis, Differential
• Female
• Humans
• Immunohistochemistry
• Myoepithelioma (chemistry, pathology, surgery)
• Predictive Value of Tests
• Solitary Fibrous Tumors (pathology)
• Vulvar Neoplasms (chemistry, pathology, surgery)