Impact of length of injecting career on HIV incidence among people who inject drugs.

Abstract

We examined the relationship between duration of injecting career and HIV seroconversion among people who inject drugs (PWID) in Vancouver, Canada. Data were derived from HIV-negative PWID enrolled in a prospective cohort study. We employed Kaplan-Meier methods and Cox regression to investigate the effect of length of time since injection drug use initiation on time to HIV seroconversion. In multivariable Cox analysis, duration of injecting career was negatively associated with time to HIV seroconversion (adjusted hazard ratio=0.82; 95% confidence interval [CI]: 0.69-0.97). Our findings highlight the need for interventions that target individuals who participate in high-risk drug use behaviors.

• Authors: Jacqueline Montain, Lianping Ti, Kanna Hayashi, Paul Nguyen, Evan Wood, Thomas Kerr
• Journal: Addictive behaviors (Addict Behav) Vol. 58 Pg. 90-4 (Jul 2016) ISSN: 1873-6327 [Electronic] England
• PMID: 26921723 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2016 Elsevier Ltd. All rights reserved.

Topics

• Adult
• British Columbia (epidemiology)
• Cohort Studies
• Female
• HIV Infections (epidemiology)
• Humans
• Incidence
• Kaplan-Meier Estimate
• Male
• Needle Sharing (statistics & numerical data)
• Proportional Hazards Models
• Prospective Studies
• Risk Factors
• Substance Abuse, Intravenous (epidemiology)
• Time Factors