Abstract | BACKGROUND: OBJECTIVE: METHODS: RESULTS: A total of 281 patients reacted to either oxidized R-limonene or oxidized linalool. Of these, 25% had concomitant reactions to both compounds, whereas 29% reacted only to oxidized R-limonene and 46% only to oxidized linalool. Of the 152 patients reacting to oxidized R-limonene, 46% reacted to oxidized linalool, whereas 35% of the 200 patients reacting to oxidized linalool also reacted to oxidized R-limonene. CONCLUSIONS: The majority of the patients (75%) reacted to only one of the oxidation mixtures, thus supporting the specificity of the reactions. The concomitant reactions to the two fragrance allergens suggest multiple sensitizations, which most likely reflect the exposure to the different fragrance materials in various types of consumer products. This is in accordance with what is generally seen for patch test reactions to fragrance materials.
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Authors | Johanna Bråred Christensson, Ann-Therese Karlberg, Klaus E Andersen, Magnus Bruze, Jeanne D Johansen, Begoña Garcia-Bravo, Ana Giménez Arnau, Chee-Leok Goh, Rosemary Nixon, Ian R White |
Journal | Contact dermatitis
(Contact Dermatitis)
Vol. 74
Issue 5
Pg. 273-80
(May 2016)
ISSN: 1600-0536 [Electronic] England |
PMID | 26918793
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Acyclic Monoterpenes
- Cyclohexenes
- Monoterpenes
- Perfume
- Terpenes
- Limonene
- linalool
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Topics |
- Acyclic Monoterpenes
- Australia
(epidemiology)
- Cohort Studies
- Cyclohexenes
(adverse effects)
- Denmark
(epidemiology)
- Dermatitis, Allergic Contact
(diagnosis, epidemiology, etiology)
- Humans
- Limonene
- Monoterpenes
(adverse effects)
- Oxidation-Reduction
- Patch Tests
- Perfume
(adverse effects)
- Singapore
(epidemiology)
- Spain
(epidemiology)
- Sweden
(epidemiology)
- Terpenes
(adverse effects)
- United Kingdom
(epidemiology)
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