[Basaloid Carcinoma of the Esophagus with Lugol-Voiding Lesions--A Case Report].

Abstract

Patients with Lugol-voiding lesions of the esophagus are frequently affected with multiple cancers. Basaloid carcinoma of the esophagus is a very rare disease characterized by growth in the submucosal layer that exhibits a submucosal tumor-like shape. There have been some reports that this type of carcinoma is biologically high-grade. We report a case of metachronous squamous cell carcinoma in situ and superficial basaloid carcinoma in the esophagus with Lugol-voiding lesions. A 63-year-old man underwent gastrectomy for gastric cancer at the age of 45 years. The subsequent surveillance endoscopy found a type 0-Ⅱc lesion in the esophagus in 2000. EMR was thus performed. The pathology showed squamous cell carcinoma in situ. Dysplasia was diagnosed based on the Lugol-voiding lesions, and EMR was performed twice. In 2014, a fourth EMR was performed after a high-grade intraepithelial neoplasia was diagnosed. The pathology showed squamous cell carcinoma in situ and a basaloid carcinoma in the lamina propria, T1a-LPM, ly0, v0, pHMX, pVM0. The patient has had no recurrence for approximately 1 year after the fourth EMR.

• Authors: Takeshi Shimakawa, Shinichi Asaka, Asako Shimazaki, Kentaro Yamaguchi, Takebumi Usui, Hajime Yokomizo, Shunichi Shiozawa, Kazuhiko Yoshimatsu, Takao Katsube, Yoshihiko Naritaka, Mariko Fujibayashi
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 42 Issue 12 Pg. 1899-901 (Nov 2015) ISSN: 0385-0684 [Print] Japan
• PMID: 26805210 (Publication Type: Case Reports, Journal Article)

Topics

• Biopsy
• Carcinoma, Squamous Cell (pathology)
• Esophageal Neoplasms (pathology)
• Esophageal Squamous Cell Carcinoma
• Esophagoscopy
• Humans
• Male
• Middle Aged
• Neoplasm Grading