HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Control of dentin/root sensitivity during non-surgical and surgical periodontal treatment.

AbstractAIM:
To determine the efficacy of a desensitizing regimen compared to a control in preventing the occurrence and/or alleviating dentin/root sensitivity (DRS) following non-surgical (NSPT) and surgical periodontal treatment (SPT).
METHODS:
Seventy-four chronic-periodontitis patients (CPP) were randomized into a test group (n = 38) using an in-office prophylaxis paste and a toothpaste at home both containing 8% arginine and calcium carbonate (Pro-Argin(™) Technology) or into a control group (n = 36) receiving a fluoride-free prophylaxis paste and a fluoride toothpaste. The examiner applied the assigned paste onto selected teeth for 3 s following NSPT and for 60 s before flap closure. Patients brushed with the assigned toothpaste twice daily throughout the study. DRS to air stimulus was assessed by the Schiff scale (0-3) and the Visual Analog Scale (VAS: 0-100 mm) six times over 17 weeks.
RESULTS:
In the test group, VAS scores significantly decreased at 8, 11 and 17 weeks from baseline (p ≤ 0.003) and Schiff scores at 8 and 11 weeks from baseline (p ≤ 0.014). The control group exhibited significant increases in VAS and Schiff during the study period (p ≤ 0.006). Marked inter-group differences were noted at all time points (p < 0.001).
CONCLUSIONS:
The combined use of desensitizing products (8% arginine and calcium carbonate) in-office and at-home prevented DRS development and maintained this effect for 17 weeks following NSPT and SPT.
AuthorsNantin Panagiota Giassin, Danae Anastasia Apatzidou, Katerina Solomou, Luis R Mateo, Fotinos S Panagakos, Antonis Konstantinidis
JournalJournal of clinical periodontology (J Clin Periodontol) Vol. 43 Issue 2 Pg. 138-46 (Feb 2016) ISSN: 1600-051X [Electronic] United States
PMID26660591 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Copyright© 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Chemical References
  • Dentin Desensitizing Agents
  • Toothpastes
  • Arginine
  • Fluorides
Topics
  • Arginine
  • Dentin
  • Dentin Desensitizing Agents
  • Dentin Sensitivity (drug therapy)
  • Double-Blind Method
  • Female
  • Fluorides
  • Follow-Up Studies
  • Humans
  • Male
  • Periodontal Diseases
  • Toothbrushing
  • Toothpastes
  • Touch
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: