Abstract | AIM: To determine the efficacy of a desensitizing regimen compared to a control in preventing the occurrence and/or alleviating dentin/root sensitivity (DRS) following non-surgical (NSPT) and surgical periodontal treatment (SPT). METHODS: Seventy-four chronic-periodontitis patients ( CPP) were randomized into a test group (n = 38) using an in-office prophylaxis paste and a toothpaste at home both containing 8% arginine and calcium carbonate ( Pro-Argin(™) Technology) or into a control group (n = 36) receiving a fluoride-free prophylaxis paste and a fluoride toothpaste. The examiner applied the assigned paste onto selected teeth for 3 s following NSPT and for 60 s before flap closure. Patients brushed with the assigned toothpaste twice daily throughout the study. DRS to air stimulus was assessed by the Schiff scale (0-3) and the Visual Analog Scale (VAS: 0-100 mm) six times over 17 weeks. RESULTS: In the test group, VAS scores significantly decreased at 8, 11 and 17 weeks from baseline (p ≤ 0.003) and Schiff scores at 8 and 11 weeks from baseline (p ≤ 0.014). The control group exhibited significant increases in VAS and Schiff during the study period (p ≤ 0.006). Marked inter-group differences were noted at all time points (p < 0.001). CONCLUSIONS: The combined use of desensitizing products (8% arginine and calcium carbonate) in-office and at-home prevented DRS development and maintained this effect for 17 weeks following NSPT and SPT.
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Authors | Nantin Panagiota Giassin, Danae Anastasia Apatzidou, Katerina Solomou, Luis R Mateo, Fotinos S Panagakos, Antonis Konstantinidis |
Journal | Journal of clinical periodontology
(J Clin Periodontol)
Vol. 43
Issue 2
Pg. 138-46
(Feb 2016)
ISSN: 1600-051X [Electronic] United States |
PMID | 26660591
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Dentin Desensitizing Agents
- Toothpastes
- Arginine
- Fluorides
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Topics |
- Arginine
- Dentin
- Dentin Desensitizing Agents
- Dentin Sensitivity
(drug therapy)
- Double-Blind Method
- Female
- Fluorides
- Follow-Up Studies
- Humans
- Male
- Periodontal Diseases
- Toothbrushing
- Toothpastes
- Touch
- Treatment Outcome
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