Abstract | BACKGROUND:
Eczema is a frequently encountered dermatologic condition characterized by inflammation resulting in erythema, scaling, induration, and lichenification. AIMS: The objective of this research was to examine the roll of botanical anti-inflammatories in alleviating the signs and symptoms of mild-to-moderate eczema. METHOD: A total of 25 subjects 18+ years of age with mild-to-moderate eczema were asked to leave all oral medications and cleansers unchanged substituting the botanical study moisturizer for all topical treatment three times daily for 2 weeks. Investigator, subject, and noninvasive assessments were obtained at baseline and week 2. RESULTS: There was a highly statistically significant (P < 0.001) improvement in investigator-assessed irritation, erythema, desquamation, roughness, dryness, lichenification, itching, and overall skin appearance after 2 weeks of botanical anti-inflammatory moisturizer use. Overall, a 79% reduction in itching was noted. Skin hydration as measured by corneometry increased 44% increase (P < 0.001). CONCLUSIONS:
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Authors | Zoe Diana Draelos |
Journal | Journal of cosmetic dermatology
(J Cosmet Dermatol)
Vol. 15
Issue 2
Pg. 117-9
(Jun 2016)
ISSN: 1473-2165 [Electronic] England |
PMID | 26596512
(Publication Type: Evaluation Study, Journal Article)
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Copyright | © 2015 Wiley Periodicals, Inc. |
Chemical References |
- Anti-Inflammatory Agents
- Nonprescription Drugs
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Topics |
- Administration, Topical
- Adult
- Anti-Inflammatory Agents
(administration & dosage)
- Biopsy, Needle
- Cohort Studies
- Eczema
(drug therapy, pathology)
- Female
- Follow-Up Studies
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Nonprescription Drugs
(administration & dosage)
- Phytotherapy
(methods)
- Pilot Projects
- Prospective Studies
- Severity of Illness Index
- Statistics, Nonparametric
- Treatment Outcome
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