[Prognostic Factors in Guillain-Barré Syndrome].

Abstract

Clinical outcome of Guillain-Barré syndrome (GBS) is poorer than may be expected, despite recent applications of plasmapheresis and IVIg. Among prognostic factors of GBS, clinical factors are more useful compared to electrophysiological or biological factors. To improve the outcome of GBS patients with poor prognoses, a worldwide prospective survey (IGOS, International GBS Outcome Study) and a Japanese prospective GBS outcome study (JGOS) have been conducted. These surveys make it possible to define biomarkers for disease activity and recovery, and to develop prognostic models to precisely predict the clinical course and outcome in individual patients in the early stage of the disease.

• Authors: Kenichi Kaida
• Journal: Brain and nerve = Shinkei kenkyu no shinpo (Brain Nerve) Vol. 67 Issue 11 Pg. 1411-9 (Nov 2015) ISSN: 1881-6096 [Print] Japan
• PMID: 26560956 (Publication Type: Journal Article, Review)

Chemical References

• Biomarkers
• Immunoglobulins, Intravenous

Topics

• Biomarkers (analysis)
• Guillain-Barre Syndrome (diagnosis, therapy)
• Humans
• Immunoglobulins, Intravenous (therapeutic use)
• Outcome Assessment, Health Care
• Prognosis
• Risk Factors