Spontaneous regression of non-small cell lung cancer that progressed after multiple chemotherapies: A case report.

Abstract

Spontaneous regression (SR) of cancer is defined as a complete or partial, temporary or permanent disappearance of all or at least some relevant parameters of malignant disease with inadequate or no treatment. SR of cancer is an extremely rare phenomenon. We report a case of a 67-year-old man who experienced SR of non-small-cell lung cancer (NSCLC), which progressed after fifth-line chemotherapy and regressed after chemotherapy ceased. Surprisingly, the primary tumor size continued to decrease for more than 13 months and his general condition markedly improved after discontinuation of the chemotherapy. To our knowledge, this is the first report of SR in a patient with NSCLC that was not responsive to a fifth round of chemotherapy.

• Authors: Chaeuk Chung, Dong Il Park, Sun Young Kim, Ju Ock Kim, Sung Soo Jung, Hee Sun Park, Jae Young Moon, Sung Min Kim, Min Ji Cho, Sang Ok Jung, Choong Sik Lee, Jeong Eun Lee
• Journal: Thoracic cancer (Thorac Cancer) Vol. 6 Issue 6 Pg. 805-7 (Nov 2015) ISSN: 1759-7706 [Print] Singapore
• PMID: 26557923 (Publication Type: Journal Article)