Abstract | OBJECTIVES: METHODS: This cross-sectional study recruited children from the Pediatric Epilepsy Clinic, Department of Pediatrics, Kalawati Saran Children Hospital, New Delhi from March 2012 to September 2012. All consecutive children diagnosed with epilepsy as per International League Against Epilepsy definition aged 3-18 years on valproate or phenytoin monotherapy for at least 6 months were enrolled at a tertiary care children's hospital in Northern India. After clinical and anthropometric evaluation (including body mass index [BMI] and waist circumference), the blood samples were analyzed for fasting serum glucose, total cholesterol, high-density lipoprotein-cholesterol, and serum triglyceride. RESULTS: Children with BMI >95(th) centile and waist circumference >90(th) centile were not significantly different among children on valproate and phenytoin monotherapy. Children on valproate had significantly higher mean serum triglyceride (96.9 mg/dL vs. 77.6 mg/dL; P < 0.001) and total cholesterol (148.3 mg/dL vs. 132.8 mg/dL; P = 0.002) levels as compared to children on phenytoin monotherapy. CONCLUSIONS:
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Authors | Aditi Dhir, Suvasini Sharma, Puneet Jain, Bhanu K Bhakhri, Satinder Aneja |
Journal | Journal of pediatric neurosciences
(J Pediatr Neurosci)
2015 Jul-Sep
Vol. 10
Issue 3
Pg. 222-6
ISSN: 1817-1745 [Print] India |
PMID | 26557161
(Publication Type: Journal Article)
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