Symptoms of Central Anticholinergic Syndrome After Glycopyrrolate Administration in a 5-Year-Old Child.

Abstract

Anesthesia-related central anticholinergic syndrome (CAS) is most commonly associated with administration of atropine or scopolamine, whereas glycopyrrolate is an extremely rare cause of CAS. Here, we report a case of CAS in a 5-year-old boy admitted to the intensive care unit. Immediately after the administration of glycopyrrolate, he became agitated and developed apnea, hypertension, tachycardia, and anuria. Although the present case describes a rare cause of CAS, it is an important reminder of an iatrogenic condition that is presumably underdiagnosed in the operating theater as well as the intensive care unit.

• Authors: Linea Natalie Toksvang, Ronni R Plovsing
• Journal: A & A case reports (A A Case Rep) Vol. 6 Issue 2 Pg. 22-4 (Jan 15 2016) ISSN: 2325-7237 [Electronic] United States
• PMID: 26513676 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Glycopyrrolate

Topics

• Anticholinergic Syndrome (etiology, pathology)
• Child, Preschool
• Fatal Outcome
• Glycopyrrolate (administration & dosage, adverse effects)
• Humans
• Male