Caregiver treatment satisfaction is improved together with children's asthma control: Prospective study for budesonide monotherapy in school-aged children with uncontrolled asthma symptoms.

Abstract

BACKGROUND:

If asthmatic children cannot obtain sufficient control of their disease, not only do they suffer from asthma symptoms, but the daily life activities of their caregivers are also disrupted. We investigated the effectiveness of an inhaled corticosteroid (ICS) for symptom control in previously ICS-untreated school-aged asthmatic children as well as caregiver treatment satisfaction (CTS).

METHODS:

A multicenter, open-label, single-arm study on 12-week ICS (budesonide Turbuhaler®) monotherapy was undertaken in subjects aged 5-15 years with bronchial asthma not treated with ICS during the previous 3 months. At 0, 4, 8, and 12 weeks after start of ICS administration, Japanese Pediatric Asthma Control Program (JPAC) scores, and CTS scores were summated and lung function measured. At weeks 0 and 12, questionnaires on caregiver anxiety were also assessed.

RESULTS:

Seventy-five patients were enrolled, and 69 assessed. Ninety percent of subjects had been treated with asthma controller medication except ICS before study enrollment. JPAC score and CTS score were improved significantly at weeks 4, 8, and 12 (p < 0.001). With regard to CTS, more than half of caregivers showed a perfect score at weeks 8 and 12. There was a significant correlation between JPAC score and CTS score. Lung function and caregiver anxiety were also improved, and good compliance with treatment was observed during the intervention.

CONCLUSIONS:

If treating ICS-untreated school-aged asthmatic children with uncontrolled symptoms, ICS monotherapy can improve CTS along with improving asthma control.

• Authors: Shigemi Yoshihara, Noriko Kanno, Hironobu Fukuda, Osamu Arisaka, Masahiko Arita, Kunio Sekine, Koichi Yamaguchi, Akira Tsuchida, Yumi Yamada, Toru Watanabe, Toshio Shimizu, Kiyoshi Nishikawa, Toshiyuki Nishimuta
• Journal: Allergology international : official journal of the Japanese Society of Allergology (Allergol Int) Vol. 64 Issue 4 Pg. 371-6 (Oct 2015) ISSN: 1440-1592 [Electronic] England
• PMID: 26433534 (Publication Type: Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2015 Japanese Society of Allergology. Production and hosting by Elsevier B.V. All rights reserved.

Chemical References

• Anti-Asthmatic Agents
• Budesonide

Topics

• Anti-Asthmatic Agents (administration & dosage, adverse effects, therapeutic use)
• Asthma (diagnosis, drug therapy, epidemiology)
• Budesonide (administration & dosage, adverse effects, therapeutic use)
• Caregivers (psychology)
• Child
• Female
• Humans
• Male
• Patient Satisfaction
• Personal Satisfaction
• Risk Factors
• Surveys and Questionnaires
• Treatment Outcome