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Continuous IV infusion of MESNA can prevent hemorrhagic cystitis in HSCT and retain MESNA concentration in urine.

AuthorsQ Jiang, H Huang, Q Liu, J Sun, H Zhou, Z Fan, Y Zhang, F Huang, Y Chai, D Xu, Y Lu, Q Wei, G Yu, X Li, M Dai, N Xu, D Zhou, H Zhao, K Shen, Q Mai, Y Zhou, F Meng
JournalBone marrow transplantation (Bone Marrow Transplant) Vol. 50 Issue 11 Pg. 1490-2 (Nov 2015) ISSN: 1476-5365 [Electronic] England
PMID26367223 (Publication Type: Comparative Study, Letter, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • Acrolein
  • Cyclophosphamide
  • Mesna
Topics
  • Acrolein (adverse effects, antagonists & inhibitors, urine)
  • Adolescent
  • Adult
  • Aged
  • Allografts
  • Biotransformation
  • Child
  • Cyclophosphamide (adverse effects, pharmacokinetics)
  • Cystitis (drug therapy, epidemiology, etiology, prevention & control)
  • Hematologic Neoplasms (therapy)
  • Hematopoietic Stem Cell Transplantation (adverse effects)
  • Hemorrhage (drug therapy, epidemiology, etiology, prevention & control)
  • Histocompatibility
  • Humans
  • Incidence
  • Infusions, Intravenous
  • Mesna (administration & dosage, therapeutic use, urine)
  • Middle Aged
  • Proportional Hazards Models
  • Prospective Studies
  • Retrospective Studies
  • Transplantation Conditioning (adverse effects, methods)
  • Young Adult

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