Abstract | AIM: MATERIALS AND METHODS: Seventy subjects with probing depth (PD) ≥5 mm were selected. Thirty-five subjects each were randomly assigned to SRP + placebo (Group 1) and SRP + SZ (Group 2). The clinical outcomes evaluated were plaque index, gingival index, clinical attachment level (CAL), and PD at baseline; 1 month, 3 months, and 6 months interval. Furthermore, microbial analysis using polymerase chain reaction was done to estimate the number of sites harboring periodontopathogens. RESULTS: Sixty four subjects were evaluated up to 6 months. At 6 months, the Group 2 resulted in greater mean reduction (4.10 mm) in PD as compared to Group 1 (1.49 mm), and also a greater mean CAL gain (4.20 mm) in Group 2 as compared to Group 1 (1.13 mm). These subjects also showed a significant reduction in the number of sites harboring periodontopathogens. CONCLUSION: The use of 3% SZ gel, when used as an adjunct to nonsurgical periodontal therapy in subjects with periodontitis, achieved better results than initial periodontal treatment alone.
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Authors | N Priyanka, Nitish Kalra, Shahab Saquib, Nitin Kudyar, Nikhil Malgaonkar, Hunny Jain, A R Pradeep |
Journal | Contemporary clinical dentistry
(Contemp Clin Dent)
2015 Jul-Sep
Vol. 6
Issue 3
Pg. 364-70
ISSN: 0976-237X [Print] India |
PMID | 26321836
(Publication Type: Journal Article)
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