Toxic shock syndrome toxin-1 (TSST-1) production in staphylococcal infections and serological implications with patients and healthy controls.

Abstract

TSST-1 production occurred in 4.6% among Staphylococcus aureus strains isolated from divergent clinical sources in South-West Hungary. Patients suffering from staphylococcal infections, whether or not harbouring TSST-1 positive strains, exhibited low anti TSST-1 titres in their acute phase sera compared to the healthy control population. A S. aureus strain isolated from toxic shock syndrome (TSS) was a high collagen binder and a low fibronectin and fibrinogen binder suggesting the role of connective tissue adhesion in colonization and low invasive property of TSS strains.

• Authors: A S Naidu, S Vörös, G Löczi, Z Kienle, B Brasch, L Emödy
• Journal: Acta microbiologica Hungarica (Acta Microbiol Hung) Vol. 36 Issue 1 Pg. 19-24 ( 1989) ISSN: 0231-4622 [Print] Hungary
• PMID: 2603642 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Bacterial Toxins
• Enterotoxins
• Fibronectins
• Immunoglobulin G
• Superantigens
• enterotoxin F, Staphylococcal
• Fibrinogen
• Collagen

Topics

• Bacterial Toxins
• Collagen (metabolism)
• Enterotoxins (biosynthesis, immunology)
• Female
• Fibrinogen (metabolism)
• Fibronectins (metabolism)
• Humans
• Immunoglobulin G (metabolism)
• Male
• Protein Binding
• Staphylococcal Infections (microbiology)
• Staphylococcus aureus (isolation & purification, metabolism)
• Superantigens