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Community Outbreak of HIV Infection Linked to Injection Drug Use of Oxymorphone--Indiana, 2015.

Abstract
On January 23, 2015, the Indiana State Department of Health (ISDH) began an ongoing investigation of an outbreak of human immunodeficiency virus (HIV) infection, after Indiana disease intervention specialists reported 11 confirmed HIV cases traced to a rural county in southeastern Indiana. Historically, fewer than five cases of HIV infection have been reported annually in this county. The majority of cases were in residents of the same community and were linked to syringe-sharing partners injecting the prescription opioid oxymorphone (a powerful oral semi-synthetic opioid analgesic). As of April 21, ISDH had diagnosed HIV infection in 135 persons (129 with confirmed HIV infection and six with preliminarily positive results from rapid HIV testing that were pending confirmatory testing) in a community of 4,200 persons.
AuthorsCaitlin Conrad, Heather M Bradley, Dita Broz, Swamy Buddha, Erika L Chapman, Romeo R Galang, Daniel Hillman, John Hon, Karen W Hoover, Monita R Patel, Andrea Perez, Philip J Peters, Pam Pontones, Jeremy C Roseberry, Michelle Sandoval, Jessica Shields, Jennifer Walthall, Dorothy Waterhouse, Paul J Weidle, Hsiu Wu, Joan M Duwve, Centers for Disease Control and Prevention (CDC)
JournalMMWR. Morbidity and mortality weekly report (MMWR Morb Mortal Wkly Rep) Vol. 64 Issue 16 Pg. 443-4 (May 01 2015) ISSN: 1545-861X [Electronic] United States
PMID25928470 (Publication Type: Journal Article)
Chemical References
  • Heroin
  • Oxymorphone
  • Methenamine
Topics
  • Adolescent
  • Adult
  • Causality
  • Coinfection (epidemiology)
  • Comorbidity
  • Disease Outbreaks
  • Female
  • HIV Infections (epidemiology)
  • Hepatitis C (epidemiology)
  • Heroin (administration & dosage)
  • Humans
  • Indiana (epidemiology)
  • Male
  • Methenamine (administration & dosage)
  • Middle Aged
  • Oxymorphone (administration & dosage)
  • Pregnancy
  • Pregnancy Complications, Infectious (epidemiology)
  • Rural Population
  • Sexual Partners
  • Substance Abuse, Intravenous (epidemiology)
  • Young Adult

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