Safety of antidiabetes medications: An update.

Abstract

Adverse iatrogenic effects of especial relevance for antidiabetes medications include hypoglycemic episodes, major adverse cardiovascular (CV) events, cancer, bone fractures, pancreatic effects, genital/urinary tract infections, and weight gain. Here, recent clinical studies addressing safety profiles of antidiabetes medications are reviewed. On balance, new prospective and population-based studies continue to indicate that the benefits of improved glucose control outweigh the risks associated with antidiabetes medications in most patients with type 2 diabetes.

• Authors: C J Bailey
• Journal: Clinical pharmacology and therapeutics (Clin Pharmacol Ther) Vol. 98 Issue 2 Pg. 185-95 (Aug 2015) ISSN: 1532-6535 [Electronic] United States
• PMID: 25820533 (Publication Type: Journal Article, Review)
• Copyright: © 2015 American Society for Clinical Pharmacology and Therapeutics.

Chemical References

• Biomarkers
• Blood Glucose
• Hypoglycemic Agents

Topics

• Animals
• Biomarkers (blood)
• Blood Glucose (drug effects, metabolism)
• Diabetes Mellitus, Type 2 (blood, diagnosis, drug therapy)
• Humans
• Hypoglycemic Agents (adverse effects)
• Patient Safety
• Risk Assessment
• Risk Factors
• Time Factors
• Treatment Outcome