A 74-year-old man complained of blood in his urine over a 1-week period beginning in early October 2013, and was examined in the urology department of our hospital. A thorough examination revealed
bladder cancer, and surgery was planned after two cycles of preoperative
gemcitabine plus
cisplatin chemotherapy. A chest computed tomography (CT) performed to evaluate the response to
chemotherapy revealed a mass in the right breast. The patient had previously complained about the same site, and mammography and ultrasonography had suggested the possibility of a malignant mammary gland
tumor. The results of aspiration cytology were Class V, and based on that finding, a diagnosis of
cancer of the right breast was made. In February 2014, we performed a
mastectomy, while preserving the pectoral muscles, along with sentinel node biopsy, total
cystectomy, urethrectomy, pelvic
lymph node dissection, and ureteroileal anastomosis. The histopathological diagnosis of the right
breast tumor was invasive
ductal carcinoma[
scirrhous carcinoma, ly (+), v (-), g (+), f (+), s (+), nuclear grade 1=atypia 2+mitosis 1, EIC (-), ICT (-), NCAT (-)]. A micrometastatic
tumor measuring approximately 1mm was observed in the sentinel lymph node. The
breast disease was classified as pT1N1mi(sn)M0, Stage IIA, and the
tumor was ER (+), PgR (+), HER2/neu (2+), and FISH (-). The
bladder cancer was diagnosed as urothelial
carcinoma, non-papillary, invasive G2>G3, pT2a; no pelvic
lymph node metastases were detected, and it was classified as pT2aN0M0, Stage II. Synchronous
male breast cancer and
bladder cancer is a very rare condition, and we report the case with a review of the literature.