[Aspects of encephalopathy in oncologic patients after chemotherapy].

Abstract

OBJECTIVE:

To study clinical presentations and neuroimaging results in post chemotherapy encephalopathy.

MATERIAL AND METHODS:

We examined 27 patients with cancer after chemotherapy (n=16) or chemoradiation (n=11).

RESULTS AND CONCLUSION:

All patients complained of memory impairment, sluggish mentality, moderate headache, fatigue, sleep disorder, irritability. Their neurologic status included different organic symptoms. Post chemotherapy encephalopathy is characterized by the combination of severe cerebral asthenia and different organic neurologic symptoms with moderate cephalgic syndrome. MRT showed single and multiple loci of gliosis in the white matter.

• Authors: N B Kholodova, V M Sotnikov, N Iu Dobrovol'skaia, Iu A Ponkratova
• Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (Zh Nevrol Psikhiatr Im S S Korsakova) Vol. 114 Issue 12 Pg. 84-88 ( 2014) ISSN: 1997-7298 [Print] Russia (Federation)
• PMID: 25726785 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Adult
• Aged
• Antineoplastic Agents (adverse effects, therapeutic use)
• Brain Diseases (chemically induced, diagnosis, physiopathology)
• Fatigue (chemically induced, diagnosis, physiopathology)
• Female
• Headache (chemically induced, diagnosis, physiopathology)
• Humans
• Male
• Middle Aged
• Neoplasms (drug therapy)
• Neuroglia (drug effects, pathology)
• Sleep Wake Disorders (chemically induced, diagnosis, physiopathology)