Rates of thromboembolism with three different mechanical heart valve prostheses: randomised study.

Abstract

In 434 operations for valvular heart disease, patients were randomised to receive Björk-Shiley, Edwards-Duromedics, or Medtronic-Hall mechanical prostheses. At a median follow-up time of 37.5 months there were no differences in hazard of death or non-embolic events. In the first six postoperative months the incidence of thromboembolism was about the same for the three valves. Subsequently, however, the incidence of thromboembolism for the Edwards-Duromedics valve was 3.9 times higher than for the Björk-Shiley valve, and for the Medtronic-Hall valve 2.6 times higher than for the Björk-Shiley valve.

• Authors: C E Kuntze, T Ebels, A Eijgelaar, J N Homan van der Heide
• Journal: Lancet (London, England) (Lancet) Vol. 1 Issue 8637 Pg. 514-7 (Mar 11 1989) ISSN: 0140-6736 [Print] England
• PMID: 2564058 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Topics

• Adult
• Aged
• Aortic Valve
• Evaluation Studies as Topic
• Female
• Follow-Up Studies
• Heart Valve Prosthesis (adverse effects, classification, mortality)
• Humans
• Male
• Middle Aged
• Mitral Valve
• Prospective Studies
• Random Allocation
• Thromboembolism (etiology, mortality)
• Time Factors