The efficacy of benorylate in postoperative dental pain.

Abstract

The efficacy of a single pre-operative dose of benorylate (4 g) was determined in a double-blind, randomized, placebo-controlled parallel study in patients undergoing removal of a single impacted lower third molar. Patients treated with benorylate 4 g reported significantly less pain between 3-6 h after dosage than those treated with placebo. Overall pain scores at 6 h were significantly less in the benorylate group than the placebo group. However, overall pain scores at 12 h did not differ significantly between treatment groups. It is concluded from this study that a single dose of benorylate 4 g given immediately prior to the removal of an impacted lower third molar provides limited pain control during the postoperative period.

• Authors: U Moore, R A Seymour, F M Williams, E Nicholson, M D Rawlins
• Journal: European journal of clinical pharmacology (Eur J Clin Pharmacol) Vol. 36 Issue 1 Pg. 35-8 ( 1989) ISSN: 0031-6970 [Print] Germany
• PMID: 2563688 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)

Chemical References

• Salicylates
• Acetaminophen

Topics

• Acetaminophen (therapeutic use)
• Adolescent
• Adult
• Double-Blind Method
• Female
• Humans
• Male
• Molar, Third (surgery)
• Pain, Postoperative (drug therapy)
• Random Allocation
• Salicylates (therapeutic use)
• Tooth Extraction
• Tooth, Impacted (surgery)