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A randomized trial of daclatasvir in combination with asunaprevir and beclabuvir in patients with chronic hepatitis C virus genotype 4 infection.

AuthorsTarek Hassanein, Karen D Sims, Michael Bennett, Norman Gitlin, Eric Lawitz, Tuan Nguyen, Lynn Webster, Zobair Younossi, Howard Schwartz, Paul J Thuluvath, Helen Zhou, Bhaskar Rege, Fiona McPhee, Nannan Zhou, Megan Wind-Rotolo, Ellen Chung, Amber Griffies, Dennis M Grasela, David F Gardiner
JournalJournal of hepatology (J Hepatol) Vol. 62 Issue 5 Pg. 1204-6 (May 2015) ISSN: 1600-0641 [Electronic] Netherlands
PMID25559328 (Publication Type: Clinical Trial, Phase II, Letter, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
Chemical References
  • 8-cyclohexyl-N-((dimethylamino)sulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-((3-methyl-3,8-diazabicyclo(3.2.1)oct-8-yl)carbonyl)cycloprop(d)indolo(2,1-a)(2)benzazepine-5-carboxamide
  • Antiviral Agents
  • Benzazepines
  • Carbamates
  • Enzyme Inhibitors
  • Imidazoles
  • Indoles
  • Isoquinolines
  • Pyrrolidines
  • Sulfonamides
  • Valine
  • daclatasvir
  • asunaprevir
Topics
  • Adult
  • Antiviral Agents (administration & dosage, adverse effects)
  • Benzazepines (administration & dosage, adverse effects)
  • Carbamates
  • Drug Monitoring
  • Drug Resistance, Viral
  • Enzyme Inhibitors (administration & dosage, adverse effects)
  • Female
  • Hepacivirus (drug effects, genetics)
  • Hepatitis C, Chronic (drug therapy, virology)
  • Humans
  • Imidazoles (administration & dosage, adverse effects)
  • Indoles (administration & dosage, adverse effects)
  • Isoquinolines (administration & dosage, adverse effects)
  • Male
  • Middle Aged
  • Pyrrolidines
  • Sulfonamides (administration & dosage, adverse effects)
  • Treatment Outcome
  • Valine (analogs & derivatives)

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