Abstract | BACKGROUND: MATERIALS AND METHODS: RESULTS: Forty patients with mesial temporal sclerosis (M: F = 27:13, mean age = 28.15 ± 10.9 years; duration of epilepsy = 12.0 ± 7.9 years) underwent anterior temporal lobe resection with amygdalohippocampectomy for drug-resistant epilepsy. Infusion of dexmedetomidine caused a transient fall in HR in 87.5% of patients and an increase in MAP in 62.5% of patients, which showed a tendency to revert back towards PreDEX values within 10 min after stopping the infusion. Sixty-five percent of the patients showed ≤25% reduction and 10% of them showed >25% reduction in HR. 47.5% of the patients showed ≤25% increase and 15% of them showed >25% increase in MAP. These changes were over a narrow range and within physiological limits. CONCLUSION: The infusion of dexmedetomidine for a short period causes reduction of HR and increase in MAP in patients, however the variations are within acceptable range.
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Authors | G Chaitanya, A Arivazhagan, Sanjib Sinha, K R Madhusudan Reddy, K Thennarasu, R D Bharath, M Bhaskara Rao, B A Chandramouli, P Satishchandra |
Journal | Journal of neurosciences in rural practice
(J Neurosci Rural Pract)
Vol. 5
Issue Suppl 1
Pg. S17-21
(Nov 2014)
ISSN: 0976-3147 [Print] United States |
PMID | 25540532
(Publication Type: Journal Article)
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