Abstract |
Understanding how steroids work has led to improved comprehension of such derangements of hormonal regulation as testicular feminization. This knowledge has found practical application in the treatment of hormone-dependent cancers. Gene therapy, albeit still too primitive to correct steroid-response defects, promises to be a future mainstay of management.
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Authors | R W Harrison 3rd, S S Lippman |
Journal | Hospital practice (Office ed.)
(Hosp Pract (Off Ed))
Vol. 24
Issue 9
Pg. 63-8, 70-1, 75-6
(Sep 15 1989)
ISSN: 8750-2836 [Print] United States |
PMID | 2549083
(Publication Type: Journal Article, Review)
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Chemical References |
- Receptors, Steroid
- Steroids
|
Topics |
- Amino Acid Sequence
- Animals
- Binding Sites
- Gene Expression Regulation
(drug effects)
- Humans
- Mammary Tumor Virus, Mouse
(drug effects, genetics)
- Mice
- Molecular Sequence Data
- Proto-Oncogenes
(drug effects)
- Receptors, Steroid
(analysis, isolation & purification, physiology)
- Steroids
(pharmacology, physiology)
- Structure-Activity Relationship
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