Investigation of the presence of canine adenovirus (CAdV) in owned dogs in Northern Italy.

Abstract

The use of a modified live canine adenovirus (CAdV) vaccine has greatly reduced the incidence of infectious canine hepatitis (ICH) in dogs. Nevertheless, cases of CAdV type 1 and 2 (CAdV-1 and CAdV-2) infection have been recently reported posing questions about the epidemiological situation of CAdV in dogs. In order to assess the presence of CAdV, samples from 51 dogs presented at a Veterinary Teaching Hospital in Bologna, Italy, for reasons unrelated with CAdV infection, were tested with a polymerase chain reaction (PCR) assay for CAdV. Thirty dogs (58.8%) were PCR positive for CAdV-2 infection and four of them (7.8%) were positive for CAdV-1. Sequence analysis performed on the obtained PCR products suggests that a genetically stable CAdV-1 strain and different CAdV-2 strains circulate in the canine population examined and that coinfections are relatively frequent.

• Authors: A Balboni, C Mollace, M Giunti, F Dondi, S Prosperi, M Battilani
• Journal: Research in veterinary science (Res Vet Sci) Vol. 97 Issue 3 Pg. 631-6 (Dec 2014) ISSN: 1532-2661 [Electronic] England
• PMID: 25468801 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2014 Elsevier Ltd. All rights reserved.

Chemical References

• Adenovirus Vaccines

Topics

• Adenoviridae Infections (epidemiology, veterinary)
• Adenovirus Vaccines (administration & dosage)
• Adenoviruses, Canine (genetics, isolation & purification)
• Animals
• Coinfection (epidemiology, veterinary, virology)
• Dog Diseases (epidemiology, virology)
• Dogs
• Italy (epidemiology)
• Polymerase Chain Reaction (veterinary)