Abstract | BACKGROUND: The fragrance compound geraniol is susceptible to autoxidation when in contact with air, and to cutaneous metabolism. In both processes, the isomeric aldehydes geranial and neral are formed. Citral consists of geranial and neral. Among patients with positive reactions to citral, we have previously detected concomitant reactions to geraniol in 85% of cases and to oxidized geraniol in 73% of cases. OBJECTIVE: PATIENTS AND METHODS: RESULTS: Twenty-six per cent of citral-positive patients reacted to oxidized geraniol, and 10.5% reacted to pure geraniol. Citral and/or its isomers gave positive reactions in 25% of the patients who reacted to pure geraniol. CONCLUSIONS:
|
Authors | Lina Hagvall, Johanna Bråred Christensson |
Journal | Contact dermatitis
(Contact Dermatitis)
Vol. 71
Issue 5
Pg. 280-8
(Nov 2014)
ISSN: 1600-0536 [Electronic] England |
PMID | 25209002
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Copyright | © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Acyclic Monoterpenes
- Monoterpenes
- Perfume
- Terpenes
- geraniol
- citral
|
Topics |
- Acyclic Monoterpenes
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Cross Reactions
- Dermatitis, Allergic Contact
(diagnosis, immunology, metabolism)
- Female
- Humans
- Male
- Middle Aged
- Monoterpenes
(adverse effects, immunology, metabolism)
- Oxidation-Reduction
- Patch Tests
- Perfume
(adverse effects, metabolism)
- Skin
(metabolism)
- Terpenes
(adverse effects, immunology, metabolism)
- Young Adult
|