Treatment of congenital pulmonary lymphangiectasia using ethiodized oil lymphangiography.

Abstract

Historically, congenital pulmonary lymphangiectasia (CPL) has had poor treatment outcomes despite aggressive therapy. There are recent reports of ethiodized oil (Lipiodol) lymphangiography successfully treating lymphatic leakage in adults. In this report, we describe two infants with CPL complicated by chylothoraces successfully treated by instillation of ethiodized oil into the lymphatic system. Congenital atresia of the thoracic duct was demonstrated on the lymphangiogram in both patients before treatment. Both patients have shown good short-term outcomes without supplemental oxygen or fat restricted diets at 9 months of age. Ethiodized oil lymphangiography represents a new treatment modality for some patients with CPL.

• Authors: M Gray, K Z Kovatis, T Stuart, E Enlow, M Itkin, M S Keller, H M French
• Journal: Journal of perinatology : official journal of the California Perinatal Association (J Perinatol) Vol. 34 Issue 9 Pg. 720-2 (Sep 2014) ISSN: 1476-5543 [Electronic] United States
• PMID: 25179384 (Publication Type: Case Reports, Journal Article)

Chemical References

• Contrast Media
• Ethiodized Oil

Topics

• Contrast Media (therapeutic use)
• Embolization, Therapeutic
• Ethiodized Oil (therapeutic use)
• Female
• Humans
• Infant
• Lung Diseases (congenital, diagnostic imaging, drug therapy)
• Lymphangiectasis (congenital, diagnostic imaging, drug therapy)
• Lymphography