Abstract |
A 5-year-old girl of African descent presented with a history of progressive painless swelling on the right side of the jaw since the past 2-3 months. Orthopantomogram showed a radiolucent lesion near the angle of the mandible. Subsequent CT scan revealed a 2 cm×2 cm radiolucent lesion with intense periosteal reaction surrounding the lesion and destruction of the overlying cortex. Radiological perplexity aroused regarding the possibility of eosinophilic granuloma or some other malignant lesion. Incisional biopsy performed and microscopy showed spindle cell tumor. Immunohistochemistry confirmed it as myofibroma. Myofibroma is a rare benign tumour involving mesenchyme. Involvement of the mandible is rare. Radiological presentation with strong periosteal reaction is a rarity and has rarely been reported in the medical literature. We conclude that intraosseous myofibroma can sometimes have strong periosteal reaction and careful radiological evaluation is a prerequisite for accurate diagnosis and to avoid unnecessary aggressive therapy.
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Authors | Birendra Rai, Evodia Ludusan, Brianán McGovern, Farhana Sharif |
Journal | BMJ case reports
(BMJ Case Rep)
Vol. 2014
(Sep 01 2014)
ISSN: 1757-790X [Electronic] England |
PMID | 25178888
(Publication Type: Case Reports, Journal Article)
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Copyright | 2014 BMJ Publishing Group Ltd. |
Chemical References |
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Topics |
- Actins
(metabolism)
- Biopsy
- Child, Preschool
- Diagnosis, Differential
- Edema
(diagnosis, etiology)
- Female
- Follow-Up Studies
- Humans
- Immunohistochemistry
- Mandible
- Mandibular Neoplasms
(complications, diagnosis, metabolism)
- Myofibroma
(complications, diagnosis, metabolism)
- Radiography, Panoramic
- Tomography, X-Ray Computed
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