Abstract | BACKGROUND AND PURPOSE: The association between vascular risk factors and dementia is of interest. Several studies have shown that cerebral small vessel disease (SVD) is associated with dementia. However, the association between cerebral large vessel disease (LVD) and dementia has not been thoroughly examined. METHODS: The Osaka Follow-up Study for Carotid Atherosclerosis, Part 2, was a prospective cohort study of cardiovascular events and dementia in which patients (n = 1106) with vascular risk factors underwent carotid ultrasound. Of these patients, 600 who had normal cognitive function were included and underwent brain magnetic resonance imaging. The presence of lacunar infarction and carotid stenosis served as markers for SVD and LVD, respectively. RESULTS: CONCLUSIONS:
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Authors | K Kitagawa, K Miwa, Y Yagita, S Okazaki, M Sakaguchi, H Mochizuki |
Journal | European journal of neurology
(Eur J Neurol)
Vol. 22
Issue 1
Pg. 187-92
(Jan 2015)
ISSN: 1468-1331 [Electronic] England |
PMID | 25164480
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2014 EAN. |
Topics |
- Aged
- Aged, 80 and over
- Carotid Stenosis
(diagnostic imaging, epidemiology)
- Comorbidity
- Dementia
(diagnosis, epidemiology)
- Female
- Follow-Up Studies
- Humans
- Japan
(epidemiology)
- Magnetic Resonance Imaging
- Male
- Middle Aged
- Risk Factors
- Stroke, Lacunar
(diagnostic imaging, epidemiology)
- Ultrasonography
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