[The clinical analysis for the whole-spine magnetic resonance imaging of axial spondyloarthritis].

Abstract

OBJECTIVE:

To investigate spinemagnetic resonance imaging(MRI) findings in patients with axial spondyloarthritis (SpA) and to analyze the correlation between imaging and clinical manifestation.

METHODS:

The clinical data of patients with axial SpA were recorded. All patients underwent whole spine MRI scanning. The MRI findings of spinal involvement were explored. Moreover, the correlation between lesions in spinal MRI and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), nocturnal pain visual analogue scale (VAS) score, back pain VAS score, global disease activity VAS score, Ankylosing Spondylitis Disease Activity score (ASDAS), erythrocyte sedimentation rate, C-reactive protein was analyzed.

RESULTS:

Thirty-three patients with axial SpA were included in this study. The image abnormalities of the spine were confirmed in 29 axial SpA patients by MRI, including Romanus lesion, Andersson lesion, the inflammation of facet joints and syndesmophyte. In correlation study, BASMI was positively correlated to the numbers of acute Romanus lesions, chronic Romanus lesions, chronic Andersson lesions and whole spinal lesions(r = 0.440, P < 0.05; r = 0.483, P < 0.05; r = 0.421, P < 0.05; r = 0.589, P < 0.05 respectively). There was a statistically significant correlation between chronic Andersson lesions and BASFI(r = 0.392, P < 0.05). But no significant associations were found between MRI lesions and other clinical findings.

CONCLUSIONS:

MRI lesions in axial SpA were associated with findings reflecting the spinal function, which can better guide the clinical treatment.

• Authors: Gui Luo, Zheng Zhao, Jian Zhu, Jianglin Zhang, Feng Huang
• Journal: Zhonghua nei ke za zhi (Zhonghua Nei Ke Za Zhi) Vol. 53 Issue 6 Pg. 464-8 (Jun 2014) ISSN: 0578-1426 [Print] China
• PMID: 25146515 (Publication Type: Journal Article)

Chemical References

• C-Reactive Protein

Topics

• C-Reactive Protein
• Humans
• Inflammation
• Magnetic Resonance Imaging
• Severity of Illness Index
• Spondylarthritis (diagnosis, pathology)
• Spondylitis, Ankylosing (diagnosis, pathology)