A retrospective analysis of the clinical efficacies of Q-switched Alexandrite and Q-switched Nd:YAG lasers in the treatment of nevus of Ota in Korean patients.
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| Abstract | BACKGROUND: While the Q-switched Alexandrite laser (QSAL) and the Q-switched neodymium: yttrium-aluminum-garnet (QSNY) laser have been widely used in treating nevus of Ota, few studies compared them. OBJECTIVE: To compare the efficacies of the QSAL and the QSNY laser in the treatment of nevus of Ota in Korean patients. METHODS AND MATERIALS: A retrospective multicenter study was conducted in 76 patients with nevus of Ota. Thirty-one patients were treated with a QSAL (5.5-8.0 J/cm(2), 4-mm spot size) and 45 patients were treated with QSNY laser (6.0-12.0 J/cm(2), 2-mm spot size). Treatment outcomes were categorized into five grades and the results were compared with the relevant variables taken into account using multivariate logistic regression analysis. RESULTS: QSAL treatment was more likely to achieve a better response compared with that with QSNY laser treatment. The odds ratio of achieving an excellent response, compared with the odds ratio of having a poor response, was 12.213-times more likely when a QSAL was used than when a QSNY laser was used (p = 0.026). CONCLUSION: The QSAL tends to be more efficient than the QSNY laser in the treatment of nevus of Ota in Korean patients. Further controlled, prospective comparison studies are needed.
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| Authors | Jae Eun Choi, Joo Bong Lee, Ki Beom Park, Bang Soon Kim, Un-Cheol Yeo, Chang Hun Huh, Jie Hoon Kim, Young Chul Kye |
| Journal | The Journal of dermatological treatment (J Dermatolog Treat) Vol. 26 Issue 3 Pg. 240-5 (Jun 2015) ISSN: 1471-1753 [Electronic] England |
| PMID | 24888365 (Publication Type: Comparative Study, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't) |
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