A Rare Presentation of Ménétrier's Disease as Gastroduodenal Intussusception.

Abstract

Ménétrier's disease is a rare cause of hypertrophic gastropathy that is usually confined to the gastric body and fundus. It is characterized by giant rugae, hypoalbuminemia, and foveolar hyperplasia. Here we report the case of a 26-year-old woman who presented with epigastric pain, postparandial nausea-vomiting, and weight loss. Paraclinic evaluation revealed hypoalbuminemia and hypochromic microcytic anemia. Gastroscopy and barium meal study showed diffuse polypoid, nodular lesions that affected the entire stomach, invaginating into the duodenum, leading to partial duodenal obstruction. The histologic, radiologic and endoscopic findings fulfilled the diagnosis of Ménétrier's disease. To the best of our knowledge, gastroduodenal intussusception by Ménétrier's disease has been rarely described in the literature.

• Authors: Mohammad Mehdi Hayatbakhsh Abbasi, Sodaif Darvish Moqaddam, Abdolreza Javadi, Moeinadin Safavi
• Journal: Middle East journal of digestive diseases (Middle East J Dig Dis) Vol. 5 Issue 1 Pg. 52-5 (Jan 2013) ISSN: 2008-5230 [Print] Iran
• PMID: 24829671 (Publication Type: Case Reports)