Saliva versus peri-implant inflammation: quantification of IL-1β in partially and totally edentulous patients.

Abstract

The aim of this study was to investigate the potential use of salivary IL1β in early-stage diagnostics of peri-implant inflammation in partially and totally edentulous patients rehabilitated with dental implants. Patients were classified according to peri-implant probing depth and bleeding upon probing in groups of healthy individuals or in groups of individuals with peri-implant inflammation. Data on plaque index, clinical attachment loss, suppuration, and mobility were also assessed. Saliva was collected without stimulation, and the levels of IL-1β were determined by ELISA. Healthy groups demonstrated significantly lower levels of IL-1β compared with the inflammation groups. No difference in IL-1β levels was observed between partially edentulous or totally edentulous patients. Salivary IL-1β may be useful for the diagnosis and monitoring of early peri-implant inflammation, particularly in edentulous patients.

• Authors: Flaviana Soares Rocha, Rainde Naiara Rezende Jesus, Fabiana Maria Soares Rocha, Camilla Cristhian Gomes Moura, Darceny Zanetta-Barbosa
• Journal: The Journal of oral implantology (J Oral Implantol) Vol. 40 Issue 2 Pg. 169-73 (Apr 2014) ISSN: 0160-6972 [Print] United States
• PMID: 24779950 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Dental Implants
• Interleukin-1beta
• Salivary Proteins and Peptides

Topics

• Dental Implants
• Dental Plaque Index
• Female
• Gingival Hemorrhage (classification)
• Humans
• Interleukin-1beta (analysis)
• Jaw, Edentulous, Partially (immunology, rehabilitation)
• Male
• Mouth, Edentulous (immunology, rehabilitation)
• Osseointegration (physiology)
• Periodontal Attachment Loss (classification)
• Periodontal Pocket (classification)
• Saliva (immunology)
• Salivary Proteins and Peptides (analysis)
• Stomatitis (diagnosis, immunology)
• Suppuration