Periodontal disease in patients with chronic coronary heart disease: Prevalence and association with cardiovascular risk factors.

Abstract

AIM:

There are reported links between periodontal disease (PD) and cardiovascular (CV) risk but data are lacking, especially from populations with established coronary heart disease (CHD). This study describes self-reported indicators of PD and associations with CV risk factors in a global stable CHD population.

METHODS AND RESULTS:

A total of 15,828 participants in the global STABILITY trial underwent a physical examination, blood sampling, and completed a lifestyle questionnaire. They reported remaining number of teeth (none, 1-14, 15-20, 21-25 or 26-32 (all)) and frequency of gum bleeding (never/rarely, sometimes, often or always). Adjusted linear and logistic regression models assessed associations between tooth loss, gum bleeding, and socioeconomic and CV risk factors. A total of 40.9% of participants had <15 remaining teeth; 16.4% had no teeth; and 25.6% reported gum bleeding with large differences in prevalence among countries, regions and ethnic groups. Less tooth loss was associated with lower levels of glucose, low-density lipoprotein (LDL) cholesterol, systolic blood pressure, waist circumference and hs-CRP; higher estimated glomerular filtration rate; decreased odds for diabetes and smoking, and increased odds for higher education, alcohol consumption and work stress. Gum bleeding was associated with higher LDL cholesterol and systolic blood pressure; decreased odds for smoking, but increased odds for higher education, alcohol consumption and stress.

CONCLUSION:

Self-reported indicators of PD were common in this chronic CHD population and were associated with an increasing socioeconomic and CV risk factor burden. However, causality between self-reported PD and CV risk and outcome needs further investigation.

• Authors: Ola Vedin, Emil Hagström, Dianne Gallup, Megan L Neely, Ralph Stewart, Wolfgang Koenig, Andrzej Budaj, Piyamitr Sritara, Lars Wallentin, Harvey D White, Claes Held
• Journal: European journal of preventive cardiology (Eur J Prev Cardiol) Vol. 22 Issue 6 Pg. 771-8 (Jun 2015) ISSN: 2047-4881 [Electronic] England
• PMID: 24721691 (Publication Type: Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
• Copyright: © The European Society of Cardiology 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Topics

• Aged
• Coronary Disease (diagnosis, epidemiology)
• Female
• Gingival Hemorrhage (diagnosis, epidemiology)
• Health Surveys
• Humans
• Life Style
• Linear Models
• Logistic Models
• Male
• Middle Aged
• Odds Ratio
• Periodontal Diseases (diagnosis, epidemiology)
• Prevalence
• Risk Factors
• Socioeconomic Factors
• Surveys and Questionnaires
• Tooth Loss (diagnosis, epidemiology)