Abstract | CONTEXT: OBJECTIVE: MATERIAL AND METHODS: An outbreak of adenovirus conjunctivitis occurred between September and December 2012 at the neonatal intensive care unit of our hospital. Forty-three infants with adenoviral conjunctivitis were examined in this study. Thirty-five eyes of 35 infants who had detailed ophthalmological examination and clinical scoring were included. The conjunctiva of 15 infants (Group 1) were irrigated with povidone iodine 2.5% solution and then treated with preservative-free artificial tears and preservative-free antibiotic drops. Twenty infants (Group 2) were treated only with the same drops with the same posology, without conjunctival irrigation with povidone iodine. Patients were examined two times a week until the complete recovery. Lid edema, conjunctival chemosis, fragility of conjunctival vasculature, pseudomembrane formation, and corneal involvement were scored clinically. RESULTS: Twenty patients (57%) were female and 15 patients (43%) were male and mean age was 3.1 months (ranged from 1 to 4 months). No relation was found between gender and clinical scores. Statistically significant lower clinical scores were obtained from Group 1. The median recovery time was earlier in Group 1 (7 d) than Group 2 (12 d) (p = 0.001). CONCLUSION:
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Authors | Zuhal Özen Tunay, Ozdemir Ozdemir, Ikbal Seza Petricli |
Journal | Cutaneous and ocular toxicology
(Cutan Ocul Toxicol)
Vol. 34
Issue 1
Pg. 12-5
(Mar 2015)
ISSN: 1556-9535 [Electronic] England |
PMID | 24678746
(Publication Type: Journal Article)
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Chemical References |
- Anti-Infective Agents, Local
- Povidone-Iodine
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Topics |
- Adenoviridae Infections
(drug therapy, epidemiology)
- Anti-Infective Agents, Local
(therapeutic use)
- Conjunctivitis, Viral
(drug therapy, epidemiology)
- Cross Infection
(drug therapy, epidemiology)
- Disease Outbreaks
- Female
- Humans
- Infant
- Intensive Care, Neonatal
- Male
- Povidone-Iodine
(therapeutic use)
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