Abstract | BACKGROUND: MATERIAL AND METHODS: We compare retrospectively RTx outcomes [graft/patient survival, rejection rates and adverse cardiac events] in study group [low left ventricular ejection fraction (LVEF) ≤ 45% by echocardiogram, n = 63] and control group [normal LVEF ≥ 50%, n = 537] from a developing country. RESULTS: The mean EF was 35 ± 5.6 and 57 ± 3% for the study and control groups, respectively (p < 0.001). Majority of these patients (98%) showed normalization of LVEF post-transplant. The median EF was 60% at 1-3 months post-transplant. No difference was noted in graft survival, patient survival, rejection rates, serum creatinine and adverse cardiac events of study group at 1.3-year mean follow-up compared to control group. Outcome was not adversely affected by preexisting LV dysfunction. The study and control groups had nearly similar percent of patients with established CAD but significantly more hospitalization for CHF pre RTx in the study group compared with the control group. CONCLUSION:
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Authors | Vivek B Kute, Aruna V Vanikar, Himanshu V Patel, Manoj R Gumber, Pankaj R Shah, Divyesh P Engineer, Manish R Balwani, Rajesh Singh Gautam, Pranjal R Modi, Veena R Shah, Hargovind L Trivedi |
Journal | Renal failure
(Ren Fail)
Vol. 36
Issue 6
Pg. 854-8
(Jul 2014)
ISSN: 1525-6049 [Electronic] England |
PMID | 24666550
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Adolescent
- Adult
- Aged
- Child
- Female
- Heart Failure
(complications, mortality, physiopathology)
- Humans
- India
(epidemiology)
- Kaplan-Meier Estimate
- Kidney Failure, Chronic
(complications, mortality, surgery)
- Kidney Transplantation
(mortality)
- Male
- Middle Aged
- Retrospective Studies
- Stroke Volume
- Young Adult
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