Multiple malignancies in a patient with limited granulomatosis with polyangiitis without immunosuppressive therapy.

Abstract

Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malignancies in a patient with limited GPA without immunosuppressive treatment. Thus, our report supports the notion that limited GPA itself can be associated with the development of malignancy.

• Authors: Yun-Hong Cheon, Min-Gyo Kim, Ji-Eun Kim, Chang Yoon Ha, Sang-Il Lee, Hyun-Ok Kim
• Journal: Modern rheumatology (Mod Rheumatol) Vol. 26 Issue 3 Pg. 450-3 ( 2016) ISSN: 1439-7609 [Electronic] England
• PMID: 24645720 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids

Topics

• Adenocarcinoma (complications)
• Aged
• Carcinoma, Papillary (complications)
• Glucocorticoids (therapeutic use)
• Granulomatosis with Polyangiitis (complications, drug therapy)
• Humans
• Male
• Myelodysplastic Syndromes (complications)
• Stomach Neoplasms (complications)
• Thyroid Neoplasms (complications)