Kleine-Levin syndrome: a case report and review of literature.

Abstract

BACKGROUND:

Kleine-Levin syndrome presents with recurrent hypersomnia along with a number of other neuropsychiatric features, of which hyperorality has not been described frequently.

METHOD:

We report a male adolescent who presented with recurrent hypersomnia, hypersexuality, and hyperorality. Magnetic resonance imaging of the brain and overnight polysomnography followed by a multiple sleep latency tests were ordered. Excessive daytime sleepiness was assessed with the Epworth Sleepiness Scale.

RESULTS:

Magnetic resonance imaging of the brain did not reveal any abnormality. Overnight video-synchronized polysomnography and multiple sleep latency tests ruled out narcolepsy. Epworth Sleepiness Scale score at baseline was 22. He was prescribed lithium carbonate 300 mg twice a day. The symptoms improved within a week after starting lithium carbonate therapy.

CONCLUSION:

Kleine-Levin syndrome may present with hyperorality, and our patient responded well to lithium carbonate therapy.

• Authors: Sourav Das, Ravi Gupta, Mohan Dhyani, Shailendra Raghuvanshi
• Journal: Pediatric neurology (Pediatr Neurol) Vol. 50 Issue 4 Pg. 411-6 (Apr 2014) ISSN: 1873-5150 [Electronic] United States
• PMID: 24630285 (Publication Type: Case Reports, Journal Article, Review)
• Copyright: Copyright © 2014 Elsevier Inc. All rights reserved.

Chemical References

• Antimanic Agents
• Lithium Carbonate

Topics

• Adolescent
• Antimanic Agents (therapeutic use)
• Brain (pathology)
• Diagnosis, Differential
• Humans
• Kleine-Levin Syndrome (diagnosis, drug therapy, pathology, physiopathology)
• Lithium Carbonate (therapeutic use)
• Magnetic Resonance Imaging
• Male