Abstract | OBJECTIVE: METHOD: RESULT: At the 7th day, the amount of RBC and HGB in model mice was significantly increased (P <0. 01) by 2 g kg-1 Paeoniae Radix Alba and 2 g kg-1 Paeoniae Radix Rubra. At the 14th day, the amount of RBC and HGB in model mice was significantly increased (P <0. 01) by 2 g kg-1 Paeoniae Radix Alba. The amount of RBC and HGB in mice treated with Paeoniae Radix Rubra had an increasing trend compared with the same dose of Paeoniae Radix Rubra, but the difference was not significant. In another experiment with the same model, the amount of RBC and HGB in model mice was significantly increased (P<0.01) by 120 mg kg-1 paeoflorin and 120 mg kg-1 albiflorin at the 7th day, meanwhile, 60 mg kg-1 and 30 mg kg-1 albiflorin also increased the amount of RBC and HGB. At the 14th day, 120 mg kg-1 paeoflorin and all doses of albiflorin increased the amount of RBC and HGB. Comepared with that of the same dose of paeoniflorin, the amount of RBC in mice was significantly increased (P <0. 05) by 30 mg kg-1 albiflorin and 120 mg kg-1 albiflorin; the amount of HGB was significantly increased (P <0. 05) by 30 mg kg -1 albiflorin. CONCLUSION:
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Authors | Jian-Jun Zhang, Yin-Feng Huang, Li-Li Wang, Wei Li, Jing-Xia Wang, Chun Wang, Sheng-Sheng Qu |
Journal | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
(Zhongguo Zhong Yao Za Zhi)
Vol. 38
Issue 19
Pg. 3358-62
(Oct 2013)
ISSN: 1001-5302 [Print] China |
PMID | 24422408
(Publication Type: Journal Article)
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Chemical References |
- Benzoates
- Bridged-Ring Compounds
- Drugs, Chinese Herbal
- Glucosides
- Hemoglobins
- Monoterpenes
- peoniflorin
- albiflorin
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Topics |
- Animals
- Benzoates
(pharmacology)
- Bridged-Ring Compounds
(pharmacology)
- Disease Models, Animal
- Drugs, Chinese Herbal
(pharmacology)
- Erythrocytes
(drug effects)
- Glucosides
(pharmacology)
- Hemoglobins
(drug effects)
- Male
- Mice
- Monoterpenes
- Paeonia
(chemistry)
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