Abstract | OBJECTIVE: this study aimed to prepare a silkworm moth (Bombyx mori) antigenic extract and to perform skin prick tests with this extract in patients with allergic respiratory diseases; to evaluate serum specific immunoglobulin E ( IgE) to Bombyx mori using ImmunoCAP® system and to report the frequency of positivity between the two methods and with clinical data. METHODS: this was a cross-sectional study with 99 children and adolescents diagnosed with asthma and/or allergic rhinitis, who had skin reactivity to at least one of the six aeroallergens tested. Clinical data were evaluated: skin prick tests with Bombyx mori in-house extract, and total and specific IgE analysis using ImmunoCAP® were performed. RESULTS: CONCLUSIONS: a high frequency of sensitization to Bombyx mori was observed in a selected population of patients with respiratory allergic diseases in the city of Curitiba, state of Paraná, Brazil. The extract prepared from the wings of this moth species is effective in demonstrating this sensitivity.
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Authors | Laura M L Araujo, Nelson A Rosário Filho, Carlos A Riedi |
Journal | Jornal de pediatria
(J Pediatr (Rio J))
2014 Mar-Apr
Vol. 90
Issue 2
Pg. 176-81
ISSN: 1678-4782 [Electronic] Brazil |
PMID | 24361294
(Publication Type: Journal Article)
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Copyright | Copyright © 2013 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved. |
Chemical References |
- Allergens
- Immunoglobulin E
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Topics |
- Adolescent
- Allergens
(immunology)
- Animals
- Asthma
(epidemiology, immunology)
- Bombyx
(immunology)
- Brazil
- Child
- Cross-Sectional Studies
- Female
- Humans
- Immunoglobulin E
(blood)
- Male
- Moths
(immunology)
- Rhinitis, Allergic
- Rhinitis, Allergic, Perennial
(epidemiology, immunology)
- Skin Tests
(methods)
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