Comparison of Locoregional Recurrence with Mastectomy vs. Breast Conserving Surgery in Pregnancy Associated Breast Cancer (PABC).

Abstract

We have compared outcomes, including the locoregional recurrence, between mastectomy and breast conserving therapy in PABC. Patients were divided into those who were treated with mastectomies (group 1) and those with breast conserving surgery (group 2). The groups were comparable except for lower mean age in group 2 and more patients with stage III disease and higher number of nodes positive in the group 1. Five-year actuarial LRR, distant metastases free survival and overall survival in group 1 vs. 2 were 10% vs. 37%, 73% vs. 81% and 57% vs. 59% respectively. The patients with PABC treated with breast conserving therapy, despite having lower stage disease, have a higher risk of local regional recurrence in comparison with those treated with mastectomy.

• Authors: Sushil Beriwal, Bunja Rungruang, Atilla Soran, Darcy Thull, Joseph L Kelley, Rohit Bhargava, Chyongchiou J Lin, Paniti Sukumvanich
• Journal: Cancers (Cancers (Basel)) Vol. 1 Issue 1 Pg. 12-20 (Dec 04 2009) ISSN: 2072-6694 [Print] Switzerland
• PMID: 24280969 (Publication Type: Journal Article)