Cat-scratch disease.

Abstract

PURPOSE:

To discuss the systemic and ocular manifestations, diagnosis and treatment of Bartonella infection.

METHOD:

Review of the literature.

RESULTS:

Bartonella are facultative intracellular Gram-negative rods that infect the erythrocytes or endothelial cells and are related to cat scratch disease (CSD). Bartonella henselae infection has localized or systemic features; the ocular diseases related to Bartonella affect 5--10% of patients with CSD. The diagnosis is based on clinical findings and laboratory tests. The indication of antibiotic therapy depends on the manifestation of the Bartonella infection, the host immunity and the patient's age.

CONCLUSION:

Physicians should look for Bartonella henselae in cases of follicular conjuntivitis and regional limphadenopathy, neuroretinitis or retinal infiltrates; currently, serological tests can confirm the clinical suspicion of this infection.

• Authors: Ana Luiza Biancardi, Andre Luiz Land Curi
• Journal: Ocular immunology and inflammation (Ocul Immunol Inflamm) Vol. 22 Issue 2 Pg. 148-54 (Apr 2014) ISSN: 1744-5078 [Electronic] England
• PMID: 24107122 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Bacterial Agents
• DNA, Bacterial

Topics

• Anti-Bacterial Agents (therapeutic use)
• Bartonella henselae (genetics, isolation & purification)
• Biopsy
• Cat-Scratch Disease (diagnosis, drug therapy, microbiology)
• DNA, Bacterial (analysis)
• Eye Infections, Bacterial (diagnosis, drug therapy, microbiology)
• Global Health
• Humans
• Incidence
• Lymph Nodes (microbiology, pathology)
• Polymerase Chain Reaction