[Cycloferon in therapy of hyperplastic laryngitis for decrease of the number of relapses].

Abstract

The article describes the clinical forms of chronic hyperplastic laryngitis, characterized by persistent and recurrent course, a tendency to the formation of oncological pathology, at the expense of hyperplastic changes in the larynx, leading to a malignancy of the inflammatory process. It was demonstrated the bacterization of larynx by Epstein-Barr virus (EBV) and Mycoplasma in imbalance of system of interferon. Clinical recovery, depending on the clinical form of the disease, using cycloferon, was observed in 57.4% of patients. The inclusion in the complex of the medical support of chronic hyperplastic laryngitis inducer of interferon - cycloferon, provided the reduction of the number of relapses.

• Authors: S S Grigorian, M G Romantsov, E V Demchenko, A L Kovalenko
• Journal: Eksperimental'naia i klinicheskaia farmakologiia (Eksp Klin Farmakol) Vol. 76 Issue 7 Pg. 39-42 ( 2013) ISSN: 0869-2092 [Print] Russia (Federation)
• PMID: 24006616 (Publication Type: Journal Article)

Chemical References

• Acridines
• Antibodies, Bacterial
• Antibodies, Viral
• Interferon Inducers
• Interferon-alpha
• Interferon-gamma
• 10-carboxymethyl-9-acridanone

Topics

• Acridines (therapeutic use)
• Antibodies, Bacterial (blood, immunology)
• Antibodies, Viral (blood, immunology)
• Chronic Disease
• Epstein-Barr Virus Infections (complications, drug therapy, immunology, pathology)
• Herpesvirus 4, Human (drug effects, physiology)
• Humans
• Hyperplasia (complications, drug therapy, immunology, pathology)
• Interferon Inducers (therapeutic use)
• Interferon-alpha (blood, immunology)
• Interferon-gamma (blood, immunology)
• Laryngitis (complications, drug therapy, immunology, pathology)
• Larynx (drug effects, immunology, pathology)
• Mycoplasma (drug effects, growth & development)
• Mycoplasma Infections (complications, drug therapy, immunology, pathology)
• Secondary Prevention