[Successful control of hyper-cortisolemia due to ACTH-producing thyroid carcinoid by laparoscopic bilateral adrenalectomy : a case report].

Abstract

A 22-year-old man was referred to our hospital because of facial edema and increasing body weight. Under the diagnosis of Cushing syndrome due to an adrenocorticotropic (ACTH)-producing thyroid tumor, thyroidectomy with regional lymph node dissection was performed. Histopathological diagnosis was thyroid carcinoid. In spite of the operation, serum ACTH and cortisol concentrations increased again due to mediastinal lymph node metastasis. His hyper-cortisolemia was resistant to drug therapy. Then, laparoscopic bilateral adrenalectomy was performed. After the operation, hyper-cortisolemia and clinical symptoms markedly improved. An additional chemotherapy is implemented because of new metastasis in the mediastinum lymph nodes.

• Authors: Yuta Kojima, Noritaka Kamimura, Hayato Yamamoto, Hiromi Murasawa, Akiko Okamoto, Atsushi Imai, Shingo Hatakeyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Chikara Ohyama
• Journal: Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 59 Issue 7 Pg. 419-22 (Jul 2013) ISSN: 0018-1994 [Print] Japan
• PMID: 23945320 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Adrenocorticotropic Hormone

Topics

• Adrenalectomy
• Adrenocorticotropic Hormone (biosynthesis)
• Carcinoid Tumor (complications)
• Cushing Syndrome (blood, etiology, surgery)
• Humans
• Laparoscopy
• Lymph Node Excision
• Male
• Thyroid Neoplasms (complications)
• Young Adult