Macrolide-resistant Mycoplasma pneumoniae pneumonia in adolescents and adults: clinical findings, drug susceptibility, and therapeutic efficacy.

Abstract

We investigated differences in the clinical findings between 30 patients with macrolide-resistant Mycoplasma pneumoniae pneumonia and 43 patients with macrolide-sensitive M. pneumoniae pneumonia in adolescents and adults. No differences in clinical presentation were observed between the two groups. Among patients with macrolide-resistant Mycoplasma pneumoniae pneumonia, treatment was more effective in the groups that received quinolones and minocycline than in the group that received macrolides (P = 0.0361 and P = 0.0237, respectively).

• Authors: Naoyuki Miyashita, Hiroto Akaike, Hideto Teranishi, Kazunobu Ouchi, Niro Okimoto
• Journal: Antimicrobial agents and chemotherapy (Antimicrob Agents Chemother) Vol. 57 Issue 10 Pg. 5181-5 (Oct 2013) ISSN: 1098-6596 [Electronic] United States
• PMID: 23896480 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Bacterial Agents
• Macrolides
• Quinolones
• Minocycline

Topics

• Adolescent
• Adult
• Anti-Bacterial Agents (pharmacology)
• Female
• Humans
• Macrolides (pharmacology)
• Male
• Microbial Sensitivity Tests
• Minocycline (pharmacology)
• Mycoplasma pneumoniae (drug effects)
• Quinolones (pharmacology)