[The use of immunoenzyme analysis in studying the etiologic structure of influenza morbidity in 1985-1988].
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| Abstract |
In the periods of epidemic increases in the incidence of influenza in 1985-1988, approximately 600 patients with clinical diagnoses of ARVI and influenza were examined for the presence of viral antigen in nasopharyngeal washings by solid-phase enzyme-immunoassay and for antibody rises in paired blood sera. The use of modified SPEIA and original test sera for influenza type A and B viruses in rapid diagnosis of influenza made it possible to decode the etiology of the epidemic situations in 1985-1988. Influenza A and B virus antigens were detected in a high portion of the examined nasopharyngeal washings. The analysis of the distribution of positive results in the detection of viral antigen in the clinical specimens and in influenza serodiagnosis demonstrated a high correlation of the results (93.9%). The etiological pattern of influenza in recent years is characterized by simultaneous circulation in the human population of influenza A (H1N1, H3N2) and B viruses, as reflected by detection of mixed infections in 1-3% of the cases.
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| Authors | E I Isaeva, Z I Rovnova, T G Poliakova, V M Stakhanova |
| Journal | Voprosy virusologii (Vopr Virusol) 1990 Mar-Apr Vol. 35 Issue 2 Pg. 119-21 ISSN: 0507-4088 [Print] Russia (Federation) |
| Vernacular Title | Primenenie immunofermentnogo analiza dlia izucheniia étiologicheskoĭ struktury zabolevaemosti grippom v 1985--1988 gg. |
| PMID | 2389565 (Publication Type: Comparative Study, English Abstract, Journal Article) |
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