Abstract | PURPOSE: Severe hemorrhage after percutaneous nephrolithotomy is a rare but alarming event. If local tamponade fails to control bleeding, the current treatment of choice is superselective renal arterial embolization. If initial embolization is unsuccessful, repeat embolization or nephrectomy is often required. To our knowledge we report the first study of risk factors for failed initial superselective renal arterial embolization. MATERIALS AND METHODS: We retrospectively reviewed the records of 17,619 patients who underwent a total of 19,185 percutaneous nephrolithotomies from January 2007 to April 2012 at 6 centers. Study inclusion criteria were percutaneous nephrolithotomy and severe postoperative renal hemorrhage requiring superselective renal arterial embolization. Data on patients in whom initial embolization failed were compared to those on patients with successful embolization on univariate and multivariate analysis. RESULTS: Of the 17,619 patients 117 (0.6%), met study inclusion criteria, including 90 males and 27 females. Initial treatment failed in 12 patients (10.3%), 8 underwent repeat superselective renal arterial embolization, 3 required 3 embolizations and 1 underwent nephrectomy. Complete bleeding cessation was achieved in all 11 repeat embolization cases. We identified 3 risk factors for failure of initial superselective renal arterial embolization, including multiple percutaneous access sites, more than 2 bleeding sites identified on renal angiogram and gelatin sponge alone used as the embolic material. CONCLUSIONS:
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Authors | Guohua Zeng, Zhenhua Zhao, Shawpong Wan, Sanjay Khadgi, Yongfu Long, Yonghai Zhang, Guocan Cao, Xiaoming Yang |
Journal | The Journal of urology
(J Urol)
Vol. 190
Issue 6
Pg. 2133-8
(Dec 2013)
ISSN: 1527-3792 [Electronic] United States |
PMID | 23831314
(Publication Type: Journal Article, Multicenter Study)
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Copyright | Copyright © 2013 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Aged
- Embolization, Therapeutic
- Female
- Humans
- Male
- Middle Aged
- Nephrostomy, Percutaneous
(adverse effects)
- Postoperative Hemorrhage
(etiology, therapy)
- Renal Artery
- Retrospective Studies
- Risk Assessment
- Risk Factors
- Severity of Illness Index
- Treatment Failure
- Young Adult
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