Rubella usually is a mild, febrile
rash illness in children and adults; however,
infection early in pregnancy, particularly during the first 16 weeks, can result in
miscarriage,
stillbirth, or an infant born with
birth defects (i.e.,
congenital rubella syndrome [CRS]). As of 2013, goals to eliminate
rubella have been established in two World Health Organization regions (the Region of the Americas by 2010 and the European Region by 2015), and targets for accelerated
rubella control and CRS prevention have been established by the Western Pacific Region (WPR). In 1976, Japan introduced single-
antigen rubella vaccine in its national immunization program, targeting girls in junior high school. In 1989, a
measles-
mumps-
rubella (
MMR) vaccine was introduced, targeting children aged 12-72 months. However, adult males remain susceptible to
rubella. From January 1 to May 1, 2013, a total of 5,442
rubella cases were reported through the
rubella surveillance system in Japan, with the majority (77%) of cases occurring among adult males. Ten infants with CRS were reported during October 2012-May 1, 2013. Countries and regions establishing a goal of accelerated control or elimination of
rubella should review their previous and current immunization policies and strategies to identify and vaccinate susceptible persons and to ensure high population immunity in all cohorts, both male and female.